Dr. Michael Wyand on The Innovation Blueprint Podcast
Oxeia CEO Dr. Michael Wyand recently sat down with Phil Therien on The Innovation Blueprint podcast for a candid conversation about concussion, OXE103, and what it actually takes to build a treatment for an injury the medical system has overlooked for decades.
Here's what he had to say about why concussion was ignored:
"There have been no concussion drugs that have ever had data submitted to the FDA. Now we know it's severe—it leads to dementia, it leads to chronic traumatic encephalopathy. But the brain, we can't see it. It's not like somebody twists their knee and they're limping. So it was ignored."
He also broke down what actually happens inside the brain:
"Shock waves cause your brain to depolarize. All the brain cells in your head just get active and fire off their energy. It's like draining the battery. The battery of the brain just drains down. And that happens instantaneously."
Oxeia's Phase 2a trial showed an 85% responder rate vs. 33% standard of care—what the company believes is the first meaningful improvement in persistent concussion symptoms from any drug candidate. The Phase 2b trial is next.
Podcast courtesy of The Innovation Blueprint and Webisoft.
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