Alex Smith Featured in Concussion Alliance: Concussions, the Threat to Football, and a Potential Concussion Medication
Listen to the interview and read the full transcript on Concussion Alliance
Oxeia Board member and former NFL star quarterback Alex Smith just sat down with Concussion Alliance to talk about his concussion history, from a ski accident at age 10 to the concussion that cost him his starting job in San Francisco, and why, after nearly 25 years of football, he believes concussions are "the biggest existential threat to American football."
On the state of concussion medicine today:
"In the background with concussions, there's nothing. There is nothing. It is a giant nothing. There's no test to even tell you if you definitively have one. This is all symptom-based… No treatment. Just nothing. Rest and wait. It's the same recommendation doctors have been giving out for over a hundred years."
On why he joined Oxeia's Board of Directors:
"To see an 85% responder rate that improved, versus a 33% who are dealing with standard of care — it was even more encouraging… A chance to do something nobody's done."
OXE103 is a form of human ghrelin, a hormone primarily produced in the gut that freely crosses the blood-brain barrier. In Oxeia's Phase 2a study, patients treated with OXE103 had improved symptom and quality-of-life scores (using the Post-Concussion Symptoms Score and the Quality of Life after Brain Injury scales) compared to those receiving standard therapy, with an 85% responder rate vs. 33% on standard of care.
Oxeia is now fundraising on StartEngine for our Phase 2b clinical trial of OXE103 (160 patients, double-blind, multi-site), targeting the underlying metabolic disruption and brain injury that follow concussion.
Join the mission to bring the first FDA-approved treatment for persistent concussion symptoms to market.
Invest nowThis Reg CF offering is made available through StartEngine Primary LLC, member FINRA/SIPC. This investment is speculative, illiquid, and involves a high degree of risk, including the possible loss of your entire investment.
